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Journal of Hand Surgery (British and European Volume)
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Oestrogen and Progesterone Hormone Receptors in Dupuytren’s Disease

F. M. HANKIN
J. ECKENRODE
D. S. LOUIS

From the University of Michigan, Ann Arbor

Dupuytren’s disease is associated with alcoholism and chronic liver disease, conditions frequently associated with deranged steroid hormone metabolism. The possible influence of endogenous sex steroid hormones on the development of Dupuytren’s disease has therefore been investigated.

An analysis of diseased palmar fascia for oestrogen and progesterone receptors was undertaken in fifteen patients. Hormone specific receptors were not found in the palmar fascia of our patients with Dupuytren’s disease, thus suggesting that other mechanisms or factors contribute to the pathogenesis of this fibrotic process.

Journal of Hand Surgery (British and European Volume), Vol. 11, No. 3, 463-464 (1986)
DOI: 10.1016/0266-7681(86)90184-1
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