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Journal of Hand Surgery (British and European Volume)
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Articles

The Neurone and Its Response to Peripheral Nerve Compression

L. B. DAHLIN
G. LUNDBORG

From the Department of Hand Surgery, University of Lund, General Hospital, Malmö, Sweden

Correspondence: Dr L. B. Dahlin, Department of Hand Surgery, General Hospital. S-214 01 Malmö, Sweden.

In all types of peripheral nerve injury, it is important to realize that the lesion affects one extended cell, the neurone, which extends from the central nervous system down to the target tissue in the extremity. Compression of a peripheral nerve can disturb the intraneural transport (axonal transport) of a large variety of substances. This may be followed by morphological and biochemical changes in the nerve cell body. These central changes may effect the axon as a whole and confer on the nerve an increased susceptibility to trauma. Studies concerning the reaction of neurones to compression, relevant when discussing the double crush syndrome, are reviewed.

Journal of Hand Surgery (British and European Volume), Vol. 15, No. 1, 5-10 (1990)
DOI: 10.1016/0266-7681(90)90040-B
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