This Article Full Text (PDF) References Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Similar articles in PubMed Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by LUNDBORG, G. Search for Related Content PubMed PubMed Citation Articles by LUNDBORG, G. Social Bookmarking                         What's this?

Neurotropism, Frozen Muscle Grafts and Other Conduits

From the Department of Hand Surgery, Lund University General Hospital, Malmö, Sweden

Correspondence: G. Lundborg, Department of Hand Surgery, General Hospital, Malmö, Sweden.

Axonal regeneration following nerve transection requires a number of cellular and biochemical phenomena in the axons as well as the nerve cell bodies. The nerve cells must survive the trauma. Since axonal severance means amputation of a large axoplasmic volume from the remaining parts of the nerve cell, the cell body must prepare for increased synthesis of axoplasm to replace the missing parts. A sprouting process must be initiated at the level of transection. Regenerating axonal processes are to regenerate towards peripheral targets, a process regulated by an interaction between genetic mechanisms in the nerve cell body and biochemical information at the molecular level along the pathway.

Journal of Hand Surgery (British and European Volume), Vol. 16, No. 5, 473-476 (1991)
DOI: 10.1016/0266-7681(91)90097-8


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?