Advanced Search

Journal Navigation

Journal Home

Subscriptions

Archive

Contact Us

Table of Contents

Sign In to gain access to subscriptions and/or personal tools.
Journal of Hand Surgery (British and European Volume)
This Article
Right arrow Full Text (PDF)
Right arrow References
Right arrow Alert me when this article is cited
Right arrow Alert me if a correction is posted
Right arrow Citation Map
Services
Right arrow Email this article to a friend
Right arrow Similar articles in this journal
Right arrow Similar articles in PubMed
Right arrow Alert me to new issues of the journal
Right arrow Add to Saved Citations
Right arrow Download to citation manager
Right arrowRequest Permissions
Right arrow Request Reprints
Right arrow Add to My Marked Citations
Citing Articles
Right arrow Citing Articles via Google Scholar
Right arrow Citing Articles via Scopus
Google Scholar
Right arrow Articles by FROSTICK, S. P.
Right arrow Articles by RADDA, G. K.
Right arrow Search for Related Content
PubMed
Right arrow PubMed Citation
Right arrow Articles by FROSTICK, S. P.
Right arrow Articles by RADDA, G. K.
Social Bookmarking
Add to CiteULike   Add to Complore   Add to Connotea   Add to Del.icio.us   Add to Digg   Add to Reddit   Add to Technorati   Add to Twitter  
What's this?

Articles

Human Muscle Cell Denervation: The Results of a 31-Phosphorus Magnetic Resonance Spectroscopy Study

S. P. FROSTICK
DORIS J. TAYLOR
M. J. DOLECKI
G. K. RADDA

From the M.R.C. Biochemical and Clinical Magnetic Resonance Unit, John Radcliffe Hospital and Radcliffe Infirmary, Oxford

Correspondence: Simon P. Frostick, D.M., M.A., F.R.C.S., Department of Orthopaedic and Accident Surgery, University of Nottingham, Queen’s Medical Centre, Nottingham NG7 2UH.

The results presented here demonstrate that there is a major abnormality of high and low energy phosphate metabolism in muscle following peripheral nerve damage. Using 31-phosphorus magnetic resonance spectroscopy the changes in phosphocreatine, adenosine triphosphate, inorganic phosphate and metabolites of membrane metabolism could be observed in vivo in human subjects. The data indicate that there may be a metabolic myopathy in the muscle cells after nerve injury. Further, the metabolic changes did not always return to the control level, indicating a persistence of the abnormality. This failure of the metabolic function of the cells may be important in determining the ultimate outcome of peripheral nerve surgery.

Journal of Hand Surgery (British and European Volume), Vol. 17, No. 1, 33-45 (1992)
DOI: 10.1016/0266-7681(92)90009-Q
Add to CiteULike CiteULike   Add to Complore Complore   Add to Connotea Connotea   Add to Del.icio.us Del.icio.us   Add to Digg Digg   Add to Reddit Reddit   Add to Technorati Technorati   Add to Twitter Twitter    What's this?