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Journal of Hand Surgery (European Volume)
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Article

EFFICIENCY OF HYALOGLIDE® IN THE PREVENTION OF THE RECURRENCE OF ADHESIONS AFTER TENOLYSIS OF FLEXOR TENDONS IN ZONE I I : A RANDOMISED, CONTROLLED, MULTICENTRE CLINICAL TRIAL : A RANDOMISED, CONTROLLED, MULTICENTRE CLINICAL TRIAL

M Riccio, Dr.1*, B Battiston2, G Pajardi3, M Corradi4, U Passaretti5, A Atzei6, M Altissimi, L Vaienti, F Catalano7, M Del Bene, P Fasolo, M Ceruso, R Luchetti, and A Landi

1 Hand Surgery and Microsurgery Unit
2 Ospedale CTO di Torino
3 Istituto MultiMedica
4 Policlinico di Parma
5 Ospedale dei Pellegrini Hand and Peripheral Nerve Surgery Unit
6 Policlinico Borgo Roma
7 Complesso Integrato Columbus

* To whom correspondence should be addressed. E-mail: michele.riccio{at}alice.it;m.riccio@ao-umbertoprimo.marche.it.


  Abstract

Hyaloglide® is a hyaluronan-based gel based on a novel auto-crosslinked technology designed to reduce postsurgical adhesions. Its efficacy was assessed in a multicentred randomised controlled trial comparing the results of flexor tenolysis in zone 2 following failed flexor tendon repairs. In the control group a standard release was performed. In the treated group, Hyaloglide® was applied into the flexor sheath and around the site of tenolysis. Forty-five patients, 19 controls and 26 treated with Hyaloglide®, were enrolled in 13 centres. All the patients were evaluated at 30, 60, 90 and 180 days after surgery by testing Total Active Motion, Quick-DASH questionnaire and number of working days lost after surgery. Patients in the Hyaloglide® group had a statistically better recovery of finger motion at all time intervals and returned earlier to work and daily activities. The use of Hyaloglide® did not appear to increase the complication rate.

First published on August 26, 2009
Journal of Hand Surgery (European Volume) 2009, doi:10.1177/1753193409342044
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