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Journal of Hand Surgery (British and European Volume)
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Articles

Does Peri-Operative Guanethidine Prevent Reflex Sympathetic Dystrophy?

C. GSCHWIND
R. FRICKER
G. LACHER
M. JUNG

From the Department of Hand Surgery, Kantonsspital, Basel, Switzerland

Correspondence: Dr C. Gschwind MD, Royal North Shore Hospital, Department of Hand Surgery, St Leonards NSW 2065, Australia.

The use of intravenous guanethidine blocks is an accepted treatment for established reflex sympathetic dystrophy (RSD). Some units administer intravenous guanethidine peri-operatively with the intention of protecting their patients from post-operative dystrophy. There have been no studies confirming this protective effect of peri-operative guanethidine. Between 1992 and 1994 we performed a prospective randomized double blind study in 71 patients undergoing fasciectomy for Duputyren’s disease. Peri-operative guanethidine did not prevent post-operative RSD in our series.

Journal of Hand Surgery (British and European Volume), Vol. 20, No. 6, 773-775 (1995)
DOI: 10.1016/S0266-7681(95)80045-X
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