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Journal of Hand Surgery (British and European Volume)
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Articles

Evidence for Immune System Involvement in Reflex Sympathetic Dystrophy

J. S. CALDER{dagger}
I. HOLTEN
R. M. R. McALLISTER

From the Blond-McIndoe Research Centre, Queen Victoria Hospital East Grinstead and St Andrews Centre for Plastic Surgery, Billericay, UK

Correspondence: R. M. R. McAllister FRCS, St Andrews Centre for Plastic Surgery, Stock Road, Billericay, Essex CMI2 0BH, UK.

Skin biopsies from patients with reflex sympathetic dystrophy were immunostained using a variety of antisera. An incidental finding with S100 staining was the presence of numerous Langerhans cells in the epidermis. All patients had significant pain at the time of biopsy, and all had symptoms refractory to treatment. The potential implications of this finding are discussed.

Journal of Hand Surgery (British and European Volume), Vol. 23, No. 2, 147-150 (1998)
DOI: 10.1016/S0266-7681(98)80162-9
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