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Journal of Hand Surgery (British and European Volume)
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Articles

A Large Family with Type IV Radial Polydactyly

A. SEYHAN, N. AKARSU and F. KESKIN

From the Department of Plastic and Reconstructive Surgery, Celal Bayar University, Manisa, (TUBITAK) DNA/Cell Bank and Gene Research Laboratory, Hacettepe University, Ankara and the Municipality Hospital, Izmir, Turkey

Correspondence: Dr A. Seyhan, Celal Bayar University, Medical Faculty, Department of Plastic and Reconstructive Surgery, 45010 Manisa, Turkey. E-mail: seyhan{at}mailcity.com

This study examines one of the largest pedigrees with radial polydactyly type IV (uncomplicated polysyndactyly) comprising a total of 69 individuals, of whom 26 have been affected over six generations. Typical manifestations of the pedigree were bilateral radial and ulnar digital duplications, as well as syndactyly between the middle and ring fingers and the second and third toes. There was no craniofacial anomaly in any of the 17 cases examined physically. This observation suggests that radial polydactyly type IV and Greig craniofacial-synostosis syndrome with similar digital manifestations are clinically-distinct entities.

Journal of Hand Surgery (British and European Volume), Vol. 23, No. 4, 530-533 (1998)
DOI: 10.1016/S0266-7681(98)80139-3
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