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Journal of Hand Surgery (British and European Volume)
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Articles

The Influence of Delay and the Effect of Fibrin Sealant on the Cut Surface of the Peripheral Nerve

An experimental study in the rat

I-M. JOU
W-C. CHEN
C-L. SHEN
H. MATSUDA

From the Department of Orthopaedics, National Cheng Kung University Medical Center, Tainan, Taiwan (ROC)

Correspondence: I-M. Jon MD, Department of Orthopaedics, National Cheng Rung University Medical Center, 138 Sheng-Li Road, Tainan, Taiwan (ROC) 704. E-mail: ntchm{at}mail.ncku.edu.tw

Thirty-two sciatic nerves in 16 rats were divided to investigate the effect of delay in fixation and the use of fibrin sealant at the site of the division on the nerve end. Specimens were assessed by morphological and morphometric criteria using scanning electron microscopy and longitudinal sections. All specimens showed a protruded nerve end. Wrapping the nerve with fibrin sealant before division and immediate fixation of the specimen resulted in less protrusion.

Journal of Hand Surgery (British and European Volume), Vol. 24, No. 6, 707-711 (1999)
DOI: 10.1054/JHSB.1999.0250
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