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Journal of Hand Surgery (British and European Volume)
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Congenital Duplication of the Palm in a Patient with Multiple Anomalies

M. M. AL-QATTAN

From the Division of Plastic Surgery, King Saud University, Riyadh, Saudi Arabia

Correspondence: M. M. Al-Qattan, FRCSC, P.O. Box 18097, Riyadh 11415, Saudi Arabia

In 1995, Parr and McMahon described a syndrome of congenital duplication of footpads in mice which lacked a protein called ‘Wingless-type mouse mammary tumour virus integration site family member 7a" (Wnt-7a). This syndrome has not been described in humans and the following report describes a similar syndrome in a Saudi girl. The role of Wnt-7a in the development of the limb along the dorso-ventral axis is discussed, along with interaction between the Wnt-7a and other axes of limb growth.

Journal of Hand Surgery (British and European Volume), Vol. 28, No. 3, 276-279 (2003)
DOI: 10.1016/S0266-7681(02)00084-0


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J Hand Surg Eur VolHome page
M. M. AL-QATTAN, M. AL-BALWI, W. EYAID, I. AL-ABDULKARIM, and S. AL-TURKI
Congenital Duplication of the Palm Syndrome: Gene Analysis and the Molecular Basis of its Clinical Features
J Hand Surg Eur Vol., April 1, 2009; 34(2): 247 - 251.
[Abstract] [Full Text] [PDF]