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Journal of Hand Surgery (British and European Volume)
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Articles

Reduction of the Incidence of Neuroma Formation By Proximal Epineural Stripping: an Experimental Study in Rats

A. M. YILDIRIM
M. I. OKUR
F. ÖZVEREN
R. ÖZERCAN

From the Department of Plastic Surgery, Neurosurgery and Pathology, Firat University Medical Faculty, Elazig, 23119, Turkey

Correspondence: Alpagan Mustafa Yildirim, Firat Üniversitesi Tip Fakültesi, Plastik Rekonstrüktif ve Estetik Cerrahi Anabilim Dali Elazig 23119, Türkiye. Tel.: +90 533 339 84 14; fax: +90 424 238 80 96.E-mail: alpagan{at}gmail.com

The effect of proximal epineural stripping on neuroma formation was studied in the peroneal nerve stumps of the rat. After transection of the peroneal nerve, the epineurium of the proximal stump was stripped back by 6 to 8 mm and the nerve fascicles left uncovered in the study group. The transected nerve was left untreated in the control group. All nerves were evaluated by light microscopy 6 months after the operation. Two neuromas occurred in 20 stumps after epineural stripping while 15 neuromas occurred in the control group. Based on histological data, we conclude that stripping of the epineurium may inhibit neuroma formation in the rat.

Key Words: neuroma • proximal epineural stripping • epineurium • rat

Journal of Hand Surgery (British and European Volume), Vol. 31, No. 4, 450-452 (2006)
DOI: 10.1016/J.JHSB.2006.04.010


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