This Article Full Text Full Text (PDF) Alert me when this article is cited Alert me if a correction is posted Services Email this article to a friend Similar articles in this journal Alert me to new issues of the journal Add to Saved Citations Download to citation manager Request Permissions Request Reprints Add to My Marked Citations Citing Articles Citing Articles via Google Scholar Citing Articles via Scopus Google Scholar Articles by BURKE, F. D. Articles by MILES, J. N. V. Search for Related Content PubMed Articles by BURKE, F. D. Articles by MILES, J. N. V. Social Bookmarking                         What's this?

An Assessment of the Effects of Exposure to Vibration, Smoking, Alcohol and Diabetes on the Prevalence of Dupuytren’s Disease in 97,537 Miners

From the Pulvertaft Hand Centre, Derbyshire Royal Infirmary, Derby, UK

Correspondence: F.D. Burke, Pulvertaft Hand Centre, Derbyshire Royal Infirmary, London Road, Derby DE1 2QY, UK., Tel.: +44 1332 290480; fax: +44 1332 291425., E-mail:frank.burke{at}virgin.net

A consecutive sample of 97,537 miners seeking compensation for Hand-Arm Vibration Syndrome were examined in a medical assessment process which included documentation of age, hand dominance, Dupuytren’s disease, years of vibration exposure, history of diabetes, smoking habits and units of alcohol consumption per week. The prime determinant of prevalence of Dupuytren’s disease was age, and all other factors investigated were corrected for age. There was no statistically significant correlation between years of exposure to vibration and the prevalence of Dupuytren’s disease. There was a statistically significant association with smoking, alcohol consumption and diabetes mellitus, with the heaviest smokers having an odds ratio (OR) of 1.31 (95% CI, 1.17, 1.47), the heaviest drinkers (in excess of 22 units a week) having an OR of 1.59 (95% CI, 1.47, 1.72) and diabetes mellitus patients having an increase in the odds of having Dupuytren’s disease of 1.52 (95% CI 1.30, 1.77).

Key Words: Dupuytren’s disease: vibration • smoking • alcohol and diabetes

Journal of Hand Surgery (European Volume), Vol. 32, No. 4, 400-406 (2007)
DOI: 10.1016/J.JHSE.2005.02.002


CiteULike    Complore    Connotea    Del.icio.us    Digg    Reddit    Technorati    Twitter    What's this?