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The Hand
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Articles

Upper-Limb-Cardiovascular Syndrome Two Cases of Holt-Oram Syndrome

YOSHIAKI YANASE
YASUO UEBA

Kyoto, Japan

Two cases of Holt-Oram syndrome with an atrial septal defect and thumb deformities are reported. The embryological basis for the association between skeletal malformations particularly of the hand, and congenital heart disease, is discussed.

The Hand, Original Series, Volume 10, No. 1, 56-60 (1978)
DOI: 10.1016/S0072-968X(78)80026-6
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